Spectronaut蛋白组学分析软件
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12/人使用者
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106/次机时次数
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7881.75/小时总时长
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0/次送样次数
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26/人收藏者
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收费标准
机时0元/小时 -
设备型号
Spectronaut 19 -
当前状态
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管理员
文美玲 Wendy Meiling WEN,郑婷 020-88338595 -
放置地点
E4-126/133走廊-132
- 仪器信息
- 预约资源
- 附件下载
- 公告
- 同类仪器
名称
Spectronaut蛋白组学分析软件
资产编号
BC-PM-0022
型号
Spectronaut 19
规格
产地
厂家
所属品牌
Biognosys
出产日期
购买日期
所属单位
生物科学中央实验室 Biosciences Central Research Facility (GZ)
使用性质
科研
所属分类
BioCRF-蛋白质&代谢组学平台 Proteomics & Metabolomics Core
资产负责人
文美玲 Wendy Meiling WEN
联系电话
020-88338595
联系邮箱
meilingwen@hkustgz.edu.cn
放置地点
E4-126/133走廊-132
- 主要规格&技术指标
- 主要功能及特色
- 设备使用相关说明
主要规格&技术指标
功能简介如下：
谱图库构建
自带 Pulsar 搜索引擎，支持 DDA、DIA、PRM（含 MS1 信息）数据建高质量库；
支持外部搜索引擎包括：Proteome Discoverer、MaxQuant、ProteinPilot 及 Mascot 检索结果建库；
深度学习辅助 iRT 保留时间矫正、decoy 预测、Pulsar 打分，进一步提升肽段鉴定量；
DIA 数据分析
支持谱图库依赖的 DIA 分析；
支持谱图库非依赖即 directDIA 分析 ；
计算机深度学习提升谱图为中心的 DIA 数据分析性能，directDIA+鉴定量显著提升（Version 17.0）与 SN16 相比，针对不同的采集类型，鉴定深度可提升 50%至 100%，并提供 FAST 和 DEEP 模式供用户选择；
支持 Ion Mobility
完全兼容 PASEF，FAIMS Pro 和 HDMS2
改进了对保留时间和离子淌度的预测算法（Version 17.0）
支持 1F Slice dia-PASEF 数据分析（Version 17.0）
支持 PTM DIA 数据分析；
支持标记定量分析（不超过 3 个通道）。
数据质控
依赖于 iRT kit 的数据质控模块，对 DIA 数据分析的同时针对质荷比、保留时间、信号强度等对 DIA
数据进行质控。
SNE 整合
应对大数据集分析。可以将大数据集拆分成多个子数据集，分别进行数据分析并生成 SNE 文件，最后在 Pipeline 视图下将多个 SNE 文件合并，输出完整报告；
统计及生物信息学分析
鉴定深度统计；
鉴定打分值统计；
样本变异系数分析；
样本相关性分析；
样本及蛋白聚类分析；
差异蛋白分析；
差异蛋白火山图；
蛋白 GO 功能注释及富集分析
报告输出
报告内容全面；
支持报告的个性化制定。
Function overview is as follows:
• Spectral Library Construction
o Comes with the Pulsar search engine, supporting DDA, DIA, and PRM (including MS1 information) for building high-quality libraries;
o Supports external search engines, including Proteome Discoverer, MaxQuant, ProteinPilot, and Mascot search results for library construction;
o Deep learning-assisted iRT retention time correction, decoy prediction, and Pulsar scoring further enhance peptide identification quantity.
• DIA Data Analysis
o Supports DIA analysis based on spectral libraries;
o Supports non-library-dependent directDIA analysis;
o Computer deep learning enhances spectral-centered DIA data analysis performance, with directDIA+ identification quantity significantly improved (Version 17.0). Compared to SN16, identification depth can increase by 50% to 100% for different acquisition types, and offers FAST and DEEP modes for user selection.
• Support for Ion Mobility
o Fully compatible with PASEF, FAIMS Pro, and HDMS2;
o Improved algorithms for predicting retention time and ion mobility (Version 17.0);
o Supports 1F Slice dia-PASEF data analysis (Version 17.0);
o Supports PTM DIA data analysis;
o Supports label-free quantification analysis (up to 3 channels).
• Data Quality Control
o Data quality control module reliant on iRT kit, performing quality control on DIA data analysis regarding mass-to-charge ratio, retention time, signal intensity, etc.
• SNE Integration
o Addresses large dataset analysis. Allows splitting large datasets into multiple sub-datasets for individual analysis and generating SNE files, which can then be merged in the Pipeline view to output a comprehensive report.
• Statistical and Bioinformatics Analysis
o Identification depth statistics;
o Identification score statistics;
o Sample coefficient of variation analysis;
o Sample correlation analysis;
o Sample and protein clustering analysis;
o Differential protein analysis;
o Differential protein volcano plots;
o Protein GO functional annotation and enrichment analysis.
• Report Output
o Comprehensive report content;
o Supports personalized report customization.
谱图库构建
自带 Pulsar 搜索引擎，支持 DDA、DIA、PRM（含 MS1 信息）数据建高质量库；
支持外部搜索引擎包括：Proteome Discoverer、MaxQuant、ProteinPilot 及 Mascot 检索结果建库；
深度学习辅助 iRT 保留时间矫正、decoy 预测、Pulsar 打分，进一步提升肽段鉴定量；
DIA 数据分析
支持谱图库依赖的 DIA 分析；
支持谱图库非依赖即 directDIA 分析 ；
计算机深度学习提升谱图为中心的 DIA 数据分析性能，directDIA+鉴定量显著提升（Version 17.0）与 SN16 相比，针对不同的采集类型，鉴定深度可提升 50%至 100%，并提供 FAST 和 DEEP 模式供用户选择；
支持 Ion Mobility
完全兼容 PASEF，FAIMS Pro 和 HDMS2
改进了对保留时间和离子淌度的预测算法（Version 17.0）
支持 1F Slice dia-PASEF 数据分析（Version 17.0）
支持 PTM DIA 数据分析；
支持标记定量分析（不超过 3 个通道）。
数据质控
依赖于 iRT kit 的数据质控模块，对 DIA 数据分析的同时针对质荷比、保留时间、信号强度等对 DIA
数据进行质控。
SNE 整合
应对大数据集分析。可以将大数据集拆分成多个子数据集，分别进行数据分析并生成 SNE 文件，最后在 Pipeline 视图下将多个 SNE 文件合并，输出完整报告；
统计及生物信息学分析
鉴定深度统计；
鉴定打分值统计；
样本变异系数分析；
样本相关性分析；
样本及蛋白聚类分析；
差异蛋白分析；
差异蛋白火山图；
蛋白 GO 功能注释及富集分析
报告输出
报告内容全面；
支持报告的个性化制定。
Function overview is as follows:
• Spectral Library Construction
o Comes with the Pulsar search engine, supporting DDA, DIA, and PRM (including MS1 information) for building high-quality libraries;
o Supports external search engines, including Proteome Discoverer, MaxQuant, ProteinPilot, and Mascot search results for library construction;
o Deep learning-assisted iRT retention time correction, decoy prediction, and Pulsar scoring further enhance peptide identification quantity.
• DIA Data Analysis
o Supports DIA analysis based on spectral libraries;
o Supports non-library-dependent directDIA analysis;
o Computer deep learning enhances spectral-centered DIA data analysis performance, with directDIA+ identification quantity significantly improved (Version 17.0). Compared to SN16, identification depth can increase by 50% to 100% for different acquisition types, and offers FAST and DEEP modes for user selection.
• Support for Ion Mobility
o Fully compatible with PASEF, FAIMS Pro, and HDMS2;
o Improved algorithms for predicting retention time and ion mobility (Version 17.0);
o Supports 1F Slice dia-PASEF data analysis (Version 17.0);
o Supports PTM DIA data analysis;
o Supports label-free quantification analysis (up to 3 channels).
• Data Quality Control
o Data quality control module reliant on iRT kit, performing quality control on DIA data analysis regarding mass-to-charge ratio, retention time, signal intensity, etc.
• SNE Integration
o Addresses large dataset analysis. Allows splitting large datasets into multiple sub-datasets for individual analysis and generating SNE files, which can then be merged in the Pipeline view to output a comprehensive report.
• Statistical and Bioinformatics Analysis
o Identification depth statistics;
o Identification score statistics;
o Sample coefficient of variation analysis;
o Sample correlation analysis;
o Sample and protein clustering analysis;
o Differential protein analysis;
o Differential protein volcano plots;
o Protein GO functional annotation and enrichment analysis.
• Report Output
o Comprehensive report content;
o Supports personalized report customization.
主要功能及特色
Spectronaut 是一款进行 DIA（Data-independent acquisition，数据非依赖采集）数据分析的商业化软件，
为 DIA 数据的分析提供完整的解决方案，包括谱图库构建、数据质控、蛋白定量、统计分析、GO 富集等。
可实现大规模实验的快速分析，最多可实现高达 10,000 个 run 的分析。具有良好的交互体验，便于初学者
上手，行业深耕者也可按需优化各项设置，达到分析目的，实现数据高质解析。
Spectronaut® is a commercial software package aimed at analyzing data independent
acquisition (DIA) proteomics experiments. Spectronaut can quantitatively profile hundreds to several thousands of proteins in one experiment. Large experiments with several conditions and replicates consisting of up to tens of thousands of LC-MS runs can be analyzed.
为 DIA 数据的分析提供完整的解决方案，包括谱图库构建、数据质控、蛋白定量、统计分析、GO 富集等。
可实现大规模实验的快速分析，最多可实现高达 10,000 个 run 的分析。具有良好的交互体验，便于初学者
上手，行业深耕者也可按需优化各项设置，达到分析目的，实现数据高质解析。
Spectronaut® is a commercial software package aimed at analyzing data independent
acquisition (DIA) proteomics experiments. Spectronaut can quantitatively profile hundreds to several thousands of proteins in one experiment. Large experiments with several conditions and replicates consisting of up to tens of thousands of LC-MS runs can be analyzed.
设备使用相关说明
最终用户声明 End-User Certification
a. 我们将作为上述产品的最终用户，包括相关软件、技术数据、服务、支持和培训（“Biognosys项目”），并仅将其用于上述描述的最终用途。
a. We will be the End User of the products described above, including related software, technical data, servicing, support, and training (the “Biognosys ltems"), and will only use them for the end use described above.
b. 我们未在美国商务部、财政部或国务院或欧盟发布的限制方名单上列出，且我们未被一个或多个列在此名单上的个人直接或间接地拥有或控制，也不受任何受制裁目的地（每个称为“限制方”）的控制或代表其行事，这种行为将违反任何适用的美国和欧盟或其他适用的贸易管制法律、法规、行政命令或指令（每个单独称为“出口管制法”）。b. We are not listed on, or owned or controlled, collectively or individually, directly or indirectly, by one or more persons listed on, a restricted parties list issued by the U.S. Departments of Commerce, Treasury, or State, or the European Union, and we are not under the control of, or acting for or on behalf of, anyone in any Embargoed Destination (each, a "Restricted Party") where such act would be in breach of any applicable U.S. and EU, or other applicable trade control law, regulation, executive order, or directive (each individually, an “Export Control Law").
c. Biognosys项目或其任何复制品将不会用于支持（i）任何核爆炸活动、未受保护的核活动或任何核燃料循环活动；或（ii）与化学、生物或核扩散、导弹、火箭系统或受限无人机系统（包括巡航导弹或目标或侦察无人机）相关的任何目的，包括但不限于意图用于战争的生物或化学剂。
c. The Biognosys ltems, or any replica thereof, will not be used to support (i) any nuclear explosive activity, unsafeguarded nuclear activity, or any nuclear fuel cycle activity; or (i) any purpose related to chemical, biological, or nuclear proliferation, missiles, rocket systems, or restricted unmanned aerial vehicle systems (including cruise missiles or target or reconnaissance drones), including but not limited to biological or chemical agents intended for warfare.
d. Biognosys项目或其任何复制品将不会用于支持（i）在中国的半导体制造设施中制造集成电路，该设施制造满足以下标准之一的集成电路（A）使用非平面架构的逻辑集成电路或具有“生产”技术节点的~16/14纳米或更小；（B）具有128层或更多的NAND记忆集成电路；或（C）使用“生产”技术节点为18纳米半间距或更小的动态随机存取记忆（DRAM）集成电路；（ii）在中国的超级计算机（如出口管理条例（“EAR”）定义）设计、开发、生产、操作、安装、维护、修理、翻新或翻修，除非根据EAR获得授权；或（iii）开发、生产或测试用于制造、检查或测试半导体器件、集成电路或电子组件的物品（包括半导体掩模、光掩模和保护膜），除非根据EAR获得授权。
d.The Biognosys ltems, or any replica thereof, will not be used to support (i) the fabrication of integrated circuits at a semiconductor fabrication facility located in China that fabricates integrated circuits that meet one of the following criteria (A)logic integrated circuits using a non-planar architecture or with a “production" technology node of~16/14 nanometers or less; (B) NOT-AND (NAND) memory integrated circuits with 128 layers or more; or (C) dynamic random-access memory (DRAM) integrated circuits using a “production" technology node of 18 nanometer half-pitch or less; (ii) the design, development, production, operation, installation, maintenance, repair overhaul, or refurbishing of a supercomputer (as defined in the Export Administration Regulations ("EAR") located in or destined to China, unless authorized under the EAR; or (iii) the development, production, or testing of items (including semiconductor masks, reticles, and pellicles) that are used to manufacture, inspect, or test semiconductor devices, integrated circuits, or electronic assemblies, unless authorized under the EAR.
a. 我们将作为上述产品的最终用户，包括相关软件、技术数据、服务、支持和培训（“Biognosys项目”），并仅将其用于上述描述的最终用途。
a. We will be the End User of the products described above, including related software, technical data, servicing, support, and training (the “Biognosys ltems"), and will only use them for the end use described above.
b. 我们未在美国商务部、财政部或国务院或欧盟发布的限制方名单上列出，且我们未被一个或多个列在此名单上的个人直接或间接地拥有或控制，也不受任何受制裁目的地（每个称为“限制方”）的控制或代表其行事，这种行为将违反任何适用的美国和欧盟或其他适用的贸易管制法律、法规、行政命令或指令（每个单独称为“出口管制法”）。b. We are not listed on, or owned or controlled, collectively or individually, directly or indirectly, by one or more persons listed on, a restricted parties list issued by the U.S. Departments of Commerce, Treasury, or State, or the European Union, and we are not under the control of, or acting for or on behalf of, anyone in any Embargoed Destination (each, a "Restricted Party") where such act would be in breach of any applicable U.S. and EU, or other applicable trade control law, regulation, executive order, or directive (each individually, an “Export Control Law").
c. Biognosys项目或其任何复制品将不会用于支持（i）任何核爆炸活动、未受保护的核活动或任何核燃料循环活动；或（ii）与化学、生物或核扩散、导弹、火箭系统或受限无人机系统（包括巡航导弹或目标或侦察无人机）相关的任何目的，包括但不限于意图用于战争的生物或化学剂。
c. The Biognosys ltems, or any replica thereof, will not be used to support (i) any nuclear explosive activity, unsafeguarded nuclear activity, or any nuclear fuel cycle activity; or (i) any purpose related to chemical, biological, or nuclear proliferation, missiles, rocket systems, or restricted unmanned aerial vehicle systems (including cruise missiles or target or reconnaissance drones), including but not limited to biological or chemical agents intended for warfare.
d. Biognosys项目或其任何复制品将不会用于支持（i）在中国的半导体制造设施中制造集成电路，该设施制造满足以下标准之一的集成电路（A）使用非平面架构的逻辑集成电路或具有“生产”技术节点的~16/14纳米或更小；（B）具有128层或更多的NAND记忆集成电路；或（C）使用“生产”技术节点为18纳米半间距或更小的动态随机存取记忆（DRAM）集成电路；（ii）在中国的超级计算机（如出口管理条例（“EAR”）定义）设计、开发、生产、操作、安装、维护、修理、翻新或翻修，除非根据EAR获得授权；或（iii）开发、生产或测试用于制造、检查或测试半导体器件、集成电路或电子组件的物品（包括半导体掩模、光掩模和保护膜），除非根据EAR获得授权。
d.The Biognosys ltems, or any replica thereof, will not be used to support (i) the fabrication of integrated circuits at a semiconductor fabrication facility located in China that fabricates integrated circuits that meet one of the following criteria (A)logic integrated circuits using a non-planar architecture or with a “production" technology node of~16/14 nanometers or less; (B) NOT-AND (NAND) memory integrated circuits with 128 layers or more; or (C) dynamic random-access memory (DRAM) integrated circuits using a “production" technology node of 18 nanometer half-pitch or less; (ii) the design, development, production, operation, installation, maintenance, repair overhaul, or refurbishing of a supercomputer (as defined in the Export Administration Regulations ("EAR") located in or destined to China, unless authorized under the EAR; or (iii) the development, production, or testing of items (including semiconductor masks, reticles, and pellicles) that are used to manufacture, inspect, or test semiconductor devices, integrated circuits, or electronic assemblies, unless authorized under the EAR.
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附件下载
公告
同类仪器
